Unfortunately Second Life is fickle and objects sometimes happen to disappear with no hope of recovery. If you were about to use a potion and you lose it, please use the form on the HUD status page on the website to report the problem. Admin will investigate and will hopefully be able to resolve the issue. However, please take into consideration the value of the potion lost when requesting a recovery. We understand that brewing potions is work and it sucks to lose one, but investigating issues is work for OOC staff as well. If the potion can be easily re-obtained through other means please seek that method first before contacting staff. Maybe even ICly play it off that the bottle rolled off the table and broke or something.
IMPORTANT - Potions should NEVER be detached from your avatar the usual way, this will result in the potion disappearing. ALWAYS click the potion and select “take” to take it back to your HUD inventory if the bottle has more uses left. You should also never log off while a potion is still attached to your avatar as this will result in the potion disappearing as well.